Ontology highlight
ABSTRACT:
SUBMITTER: Dong Y
PROVIDER: S-EPMC4396244 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Dong Yuling Y Tan Qiufen Q Tao Lin L Pan Xiaolin X Pang Lijuan L Liang Weihua W Liu Wei W Zhang Wenjie W Li Feng F Jia Wei W
International journal of clinical and experimental pathology 20150201 2
Tissue factor pathway inhibitor 2 (TFPI2) is a Kunitz-type serine proteinase inhibitor, which plays an important role in the etiology of human malignancies. DNA methylation is a common epigenetic modification of the genome that is involved in regulating many cellular processes. In addition to human papilloma virus (HPV) infection, DNA methylation may play a role in the carcinogenesis of cervical cancer. Methylation of 22 CpG sites in the promoter region of the TFPI2 gene was detected by MassARRA ...[more]