Ontology highlight
ABSTRACT:
SUBMITTER: Gao W
PROVIDER: S-EPMC4399974 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Gao Weiwei W Fang Ronnie H RH Thamphiwatana Soracha S Luk Brian T BT Li Jieming J Angsantikul Pavimol P Zhang Qiangzhe Q Hu Che-Ming J CM Zhang Liangfang L
Nano letters 20150126 2
Synthetic nanoparticles coated with cellular membranes have been increasingly explored to harness natural cell functions toward the development of novel therapeutic strategies. Herein, we report on a unique bacterial membrane-coated nanoparticle system as a new and exciting antibacterial vaccine. Using Escherichia coli as a model pathogen, we collect bacterial outer membrane vesicles (OMVs) and successfully coat them onto small gold nanoparticles (AuNPs) with a diameter of 30 nm. The resulting b ...[more]