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Refinement of whole-genome multilocus sequence typing analysis by addressing gene paralogy.


ABSTRACT: We developed a user-friendly program, Genome Profiler (GeP), to refine whole-genome multilocus sequence typing analysis by addressing gene paralogy with conserved gene neighborhoods. In comparison to similar programs, GeP produced overall the best results in terms of accuracy and is thus a useful alternative to resolve relationships of bacterial isolates.

SUBMITTER: Zhang J 

PROVIDER: S-EPMC4400783 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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Refinement of whole-genome multilocus sequence typing analysis by addressing gene paralogy.

Zhang Ji J   Halkilahti Jani J   Hänninen Marja-Liisa ML   Rossi Mirko M  

Journal of clinical microbiology 20150318 5


We developed a user-friendly program, Genome Profiler (GeP), to refine whole-genome multilocus sequence typing analysis by addressing gene paralogy with conserved gene neighborhoods. In comparison to similar programs, GeP produced overall the best results in terms of accuracy and is thus a useful alternative to resolve relationships of bacterial isolates. ...[more]

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