Ontology highlight
ABSTRACT:
SUBMITTER: Vieira AR
PROVIDER: S-EPMC4401694 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Vieira Alexandre R AR Gibson Carolyn W CW Deeley Kathleen K Xue Hui H Li Yong Y
PloS one 20150417 4
Dental caries continues to be the most prevalent bacteria-mediated non-contagious disease of humankind. Dental professionals assert the disease can be explained by poor oral hygiene and a diet rich in sugars but this does not account for caries free individuals exposed to the same risk factors. In order to test the hypothesis that amount of amelogenin during enamel development can influence caries susceptibility, we generated multiple strains of mice with varying levels of available amelogenin d ...[more]