Ontology highlight
ABSTRACT:
SUBMITTER: Ramasubramanyan S
PROVIDER: S-EPMC4402532 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Ramasubramanyan Sharada S Osborn Kay K Al-Mohammad Rajaei R Naranjo Perez-Fernandez Ijiel B IB Zuo Jianmin J Balan Nicolae N Godfrey Anja A Patel Harshil H Peters Gordon G Rowe Martin M Jenner Richard G RG Sinclair Alison J AJ
Nucleic acids research 20150316 7
Lytic replication of the human gamma herpes virus Epstein-Barr virus (EBV) is an essential prerequisite for the spread of the virus. Differential regulation of a limited number of cellular genes has been reported in B-cells during the viral lytic replication cycle. We asked whether a viral bZIP transcription factor, Zta (BZLF1, ZEBRA, EB1), drives some of these changes. Using genome-wide chromatin immunoprecipitation coupled to next-generation DNA sequencing (ChIP-seq) we established a map of Zt ...[more]