Ontology highlight
ABSTRACT:
SUBMITTER: Justice J
PROVIDER: S-EPMC4403454 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Justice James J Malhotra Sanandan S Ruano Miguel M Li Yingying Y Zavala Guillermo G Lee Nathan N Morgan Robin R Beemon Karen K
Journal of virology 20150211 9
<h4>Unlabelled</h4>Avian leukosis virus subgroup J (ALV-J) is a simple retrovirus that can cause hemangiomas and myeloid tumors in chickens and is currently a major economic problem in Asia. Here we characterize ALV-J strain PDRC-59831, a newly studied U.S. isolate of ALV-J. Five-day-old chicken embryos were infected with this virus, and the chickens developed myeloid leukosis and hemangiomas within 2 months after hatching. To investigate the mechanism of pathogenesis, we employed high-throughpu ...[more]