Toll-like receptor signaling in vertebrates: testing the integration of protein, complex, and pathway data in the protein ontology framework.
Ontology highlight
ABSTRACT:
SUBMITTER: Arighi C
PROVIDER: S-EPMC4404318 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Toll-like receptor signaling in vertebrates: testing the integration of protein, complex, and pathway data in the protein ontology framework.
Arighi Cecilia C Shamovsky Veronica V Masci Anna Maria AM Ruttenberg Alan A Smith Barry B Natale Darren A DA Wu Cathy C D'Eustachio Peter P
PloS one 20150420 3
The Protein Ontology (PRO) provides terms for and supports annotation of species-specific protein complexes in an ontology framework that relates them both to their components and to species-independent families of complexes. Comprehensive curation of experimentally known forms and annotations thereof is expected to expose discrepancies, differences, and gaps in our knowledge. We have annotated the early events of innate immune signaling mediated by Toll-Like Receptor 3 and 4 complexes in human, ...[more]
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