Ontology highlight
ABSTRACT:
SUBMITTER: D'Amico E
PROVIDER: S-EPMC4404413 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
D'Amico Eva E Gayral Stéphanie S Massart Claude C Van Sande Jacqueline J Reiter Jeremy F JF Dumont Jacques E JE Robaye Bernard B Schurmans Stéphane S
Journal of molecular endocrinology 20130423 3
Kinesins, including the kinesin 2/KIF3 molecular motor, play an important role in intracellular traffic and can deliver vesicles to distal axon terminals, to cilia, to nonpolarized cell surfaces or to epithelial cell basolateral membranes, thus taking part in the establishment of cellular polarity. We report here the consequences of kinesin 2 motor inactivation in the thyroid of 3-week-old Kif3a(Δ)(/flox) Pax8(Cre/)(+) mutant mice. Our results indicate first that 3-week-old Pax8(Cre/)(+) mice us ...[more]