Ontology highlight
ABSTRACT:
SUBMITTER: Montali A
PROVIDER: S-EPMC4405441 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Montali Anna A Truglio Gessica G Martino Francesco F Ceci Fabrizio F Ferraguti Giampiero G Ciociola Ester E Maranghi Marianna M Gianfagna Francesco F Iacoviello Licia L Strom Roberto R Lucarelli Marco M Arca Marcello M
PloS one 20150421 4
The precursors of atherogenic dyslipidemia (AD) are not well defined. Therefore, we investigated 62 non-obese, non-diabetic AD and 221 normolipemic children. Anthropometric parameters, blood pressure and biochemical measures were obtained in index children, their parents and all available siblings. The heritability (h(2)) of anthropometric and biochemical traits was estimated by SOLAR. Rare and common variants in APOA1 and LPL genes were screened by re-sequencing. Compared to normolipemic, AD ch ...[more]