Ontology highlight
ABSTRACT:
SUBMITTER: Kim BC
PROVIDER: S-EPMC4406278 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kim Byoung-Chul BC Jeong Hyoung Oh HO Park Daeui D Kim Chul-Hong CH Lee Eun Kyeong EK Kim Dae Hyun DH Im Eunok E Kim Nam Deuk ND Lee Sunghoon S Yu Byung Pal BP Bhak Jong J Chung Hae Young HY
Cancer informatics 20150420
The purpose of our study is to identify epigenetic markers that are differently expressed in the stomach adenocarcinoma (STAD) condition. Based on data from The Cancer Genome Atlas (TCGA), we were able to detect an age-related difference in methylation patterns and changes in gene and miRNA expression levels in young (n = 14) and old (n = 70) STAD subjects. Our analysis identified 323 upregulated and 653 downregulated genes in old STAD subjects. We also found 76 miRNAs with age-related expressio ...[more]