Ontology highlight
ABSTRACT:
SUBMITTER: Rau CD
PROVIDER: S-EPMC4406340 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Current opinion in cardiology 20150501 3
<h4>Purpose of review</h4>In contrast to many other human diseases, the use of genome-wide association studies (GWAS) to identify genes for heart failure (HF) has had limited success. We will discuss the underlying challenges as well as potential new approaches to understanding the genetics of common forms of HF.<h4>Recent findings</h4>Recent research using intermediate phenotypes, more detailed and quantitative stratification of HF symptoms, founder populations and novel animal models has begun ...[more]