Estimating the population distribution of usual 24-hour sodium excretion from timed urine void specimens using a statistical approach accounting for correlated measurement errors.

ABSTRACT:

Background

High US sodium intake and national reduction efforts necessitate developing a feasible and valid monitoring method across the distribution of low-to-high sodium intake.

Objective

We examined a statistical approach using timed urine voids to estimate the population distribution of usual 24-h sodium excretion.

Methods

A sample of 407 adults, aged 18-39 y (54% female, 48% black), collected each void in a separate container for 24 h; 133 repeated the procedure 4-11 d later. Four timed voids (morning, afternoon, evening, overnight) were selected from each 24-h collection. We developed gender-specific equations to calibrate total sodium excreted in each of the one-void (e.g., morning) and combined two-void (e.g., morning + afternoon) urines to 24-h sodium excreti

SUBMITTER: Wang CY 

PROVIDER: S-EPMC4408737 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature