Ontology highlight
ABSTRACT:
SUBMITTER: Sun HB
PROVIDER: S-EPMC4408775 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Sun Hui B HB Andarawis-Puri Nelly N Li Yonghui Y Fung David T DT Lee Jonathan Y JY Wang Vincent M VM Basta-Pljakic Jelena J Leong Daniel J DJ Sereysky Jedd B JB Ros Stephen J SJ Klug Raymond A RA Braman Jonathan J Schaffler Mitch B MB Jepsen Karl J KJ Flatow Evan L EL
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20101001 10
Expression profiling of selected matrix remodeling genes was conducted to evaluate differences in molecular response to low-cycle (100) and high-cycle (7,200) sub-failure-fatigue loading of patellar tendons. Using our previously developed in vivo patellar tendon model, tendons were loaded for 100 or 7,200 cycles and expression of selected metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), and collagens were quantified by real-time RT-PCR at 1- and 7-day post-loading. Exp ...[more]