Global spectrum of copy number variations reveals genome organizational plasticity and proposes new migration routes.
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ABSTRACT:
SUBMITTER: Veerappa AM
PROVIDER: S-EPMC4409114 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Global spectrum of copy number variations reveals genome organizational plasticity and proposes new migration routes.
Veerappa Avinash M AM Vishweswaraiah Sangeetha S Lingaiah Kusuma K Murthy Megha M Suresh Raviraj V RV Manjegowda Dinesh S DS Ramachandra Nallur B NB
PloS one 20150424 4
Global spectrum of CNVs is required to catalog variations to provide a high-resolution on the dynamics of genome-organization and human migration. In this study, we performed genome-wide genotyping using high-resolution arrays and identified 44,109 CNVs from 1,715 genomes across 12 populations. The study unraveled the force of independent evolutionary dynamics on genome-organizational plasticity across populations. We demonstrated the use of CNV tool to study human migration and identified a sec ...[more]
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