Genome variability and gene content in chordopoxviruses: dependence on microsatellites.
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ABSTRACT:
SUBMITTER: Hatcher EL
PROVIDER: S-EPMC4411693 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
Genome variability and gene content in chordopoxviruses: dependence on microsatellites.
Hatcher Eneida L EL Wang Chunlin C Lefkowitz Elliot J EJ
Viruses 20150422 4
To investigate gene loss in poxviruses belonging to the Chordopoxvirinae subfamily, we assessed the gene content of representative members of the subfamily, and determined whether individual genes present in each genome were intact, truncated, or fragmented. When nonintact genes were identified, the early stop mutations (ESMs) leading to gene truncation or fragmentation were analyzed. Of all the ESMs present in these poxvirus genomes, over 65% co-localized with microsatellites-simple sequence nu ...[more]
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