Occupational exposure to chemotherapy of pharmacy personnel at a single centre.

ABSTRACT:

Background

Cyclophosphamide is one of the most commonly used chemotherapy drugs worldwide. Data concerning environmental contamination and biological exposure of pharmacy personnel to this and other chemotherapy drugs are limited.

Objectives

To determine whether pharmacy personnel involved in preparing and checking cyclophosphamide doses were more likely to have detectable levels of this drug in their urine than non-oncology pharmacy personnel with no known contact with the drug, and to compare the degree of surface contamination with cyclophosphamide, methotrexate, and ifosfamide in the oncology pharmacy of a tertiary care pediatric hospital, where chemotherapy doses were prepared, and the main (control) pharmacy in the same institution, where no chemotherapy was prepared.<

SUBMITTER: Ramphal R 

PROVIDER: S-EPMC4414071 | biostudies-literature | 2015 Mar-Apr

REPOSITORIES: biostudies-literature