Dataset Information

Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy.

ABSTRACT: To determine the prevalence of and risk factors for postprandial hypoglycemic symptoms among bariatric surgery patients.A questionnaire including the Edinburgh hypoglycemia scale was mailed to patients who underwent either Roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG) at a single center. Based on the questionnaire, the patients were categorized as having high or low suspicion for post surgical, postprandial hypoglycemic symptoms.Of the 1119 patients with valid addresses, 40.2% (N?=?450) responded. Among the respondents, 34.2% had a high suspicion for symptoms of post bariatric surgery hypoglycemia. In multivariate analyses, in addition to female sex (P?=?0.001), RYGB (P?=?0.004), longer time since surgery (P?=?0.013), and lack of diabetes (P?=?0.040), the high suspicion group was more likely to report pre-operative symptoms of hypoglycemia (P?

SUBMITTER: Lee CJ

PROVIDER: S-EPMC4414701 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy.

Lee Clare J CJ Clark Jeanne M JM Schweitzer Michael M Magnuson Thomas T Steele Kimberley K Koerner Olivia O Brown Todd T TT

Obesity (Silver Spring, Md.) 20150410 5

<h4>Objective</h4>To determine the prevalence of and risk factors for postprandial hypoglycemic symptoms among bariatric surgery patients.<h4>Methods</h4>A questionnaire including the Edinburgh hypoglycemia scale was mailed to patients who underwent either Roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG) at a single center. Based on the questionnaire, the patients were categorized as having high or low suspicion for post surgical, postprandial hypoglycemic symptoms.<h4>Result ...[more]

PMID: 25866150

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Project description:BackgroundPregnancies occurring after bariatric surgery are associated with various perinatal complications. However, there may be differences in the type of perinatal complications occurring after different methods of bariatric surgery. The aim of the current study was to compare adverse perinatal outcomes in pregnant women following Roux-en-Y Gastric Bypass (RYGB) vs. Sleeve Gastrectomy (SG).MethodsA systematic database search was performed in PubMed, Embase, Scopus and CINAHL. Observational studies comparing perinatal outcomes post-bariatric (RYGB and SG) surgery to pregnancies without prior surgery were selected. Outcomes of interest were: maternal body mass index (BMI) at the time of conception, mode of delivery, time from surgery to conception, birth weight, gestational age and intrauterine fetal death. Article selection, risk of bias assessment and data extraction, were performed by two authors. The study protocol was published in its revised form in PROSPERO, registration number: CRD42021234480.ResultsA total of 3201 records were extracted. After duplicates were removed, 3143 records were screened for inclusion. Six studies fitted the selection criteria, of which four studies were RYGB and two SG (1100 post-RYGB vs. 209 post-SG). For the included studies, higher incidence of both SGA (22.9%, 11.9%, 14.2%) and LGA (4.2%, 4.8%, 1.7%) in SG compared to Roux-en-Y (SGA: 8.8%, 7.7%, 11.5%, 8.3% and LGA: 3.4%, 0.7%) were observed. SG had a shorter surgery to conception interval as compared to RYGB. Risk of bias assessment was moderate to serious for the studies included in the review, with bias in selection of participants being the major reason.ConclusionOur systematic review demonstrated no major differences in BMI, mode of delivery, birthweight, gestational age, or rates of intrauterine death between women having undergone RYGB vs. SG. The rate of SGA and LGA births were higher in the SG group, but this group also had a shorter surgery to conception interval. Future studies are indicated to counsel women of reproductive age on the most appropriate type of bariatric surgery that is associated with the best perinatal outcomes.

Dataset Information

Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy.

Publications

Prevalence of and risk factors for hypoglycemic symptoms after gastric bypass and sleeve gastrectomy.

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