Ontology highlight
ABSTRACT:
SUBMITTER: Dailey HA
PROVIDER: S-EPMC4414794 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Dailey Harry A HA Gerdes Svetlana S
Archives of biochemistry and biophysics 20150221
Genes for chlorite dismutase-like proteins are found widely among heme-synthesizing bacteria and some Archaea. It is now known that among the Firmicutes and Actinobacteria these proteins do not possess chlorite dismutase activity but instead are essential for heme synthesis. These proteins, named HemQ, are iron-coproporphyrin (coproheme) decarboxylases that catalyze the oxidative decarboxylation of coproheme III into protoheme IX. As purified, HemQs do not contain bound heme, but readily bind ex ...[more]