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Riboswitch finder--a tool for identification of riboswitch RNAs.


ABSTRACT: We describe a dedicated RNA motif search program and web server to identify RNA riboswitches. The Riboswitch finder analyses a given sequence using the web interface, checks specific sequence elements and secondary structure, calculates and displays the energy folding of the RNA structure and runs a number of tests including this information to determine whether high-sensitivity riboswitch motifs (or variants) according to the Bacillus subtilis type are present in the given RNA sequence. Batch-mode determination (all sequences input at once and separated by FASTA format) is also possible. The program has been implemented and is available both as local software for in-house installation and as a web server at http://www.biozentrum.uni-wuerzburg.de/bioinformatik/Riboswitch/.

SUBMITTER: Bengert P 

PROVIDER: S-EPMC441490 | biostudies-literature | 2004 Jul

REPOSITORIES: biostudies-literature

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Riboswitch finder--a tool for identification of riboswitch RNAs.

Bengert Peter P   Dandekar Thomas T  

Nucleic acids research 20040701 Web Server issue


We describe a dedicated RNA motif search program and web server to identify RNA riboswitches. The Riboswitch finder analyses a given sequence using the web interface, checks specific sequence elements and secondary structure, calculates and displays the energy folding of the RNA structure and runs a number of tests including this information to determine whether high-sensitivity riboswitch motifs (or variants) according to the Bacillus subtilis type are present in the given RNA sequence. Batch-m  ...[more]

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