AUGUSTUS: a web server for gene finding in eukaryotes.
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ABSTRACT:
SUBMITTER: Stanke M
PROVIDER: S-EPMC441517 | biostudies-literature | 2004 Jul
REPOSITORIES: biostudies-literature
Publications
AUGUSTUS: a web server for gene finding in eukaryotes.
Stanke Mario M Steinkamp Rasmus R Waack Stephan S Morgenstern Burkhard B
Nucleic acids research 20040701 Web Server issue
We present a www server for AUGUSTUS, a novel software program for ab initio gene prediction in eukaryotic genomic sequences. Our method is based on a generalized Hidden Markov Model with a new method for modeling the intron length distribution. This method allows approximation of the true intron length distribution more accurately than do existing programs. For genomic sequence data from human and Drosophila melanogaster, the accuracy of AUGUSTUS is superior to existing gene-finding approaches. ...[more]
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