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Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles.


ABSTRACT: Hexamodal imaging using simple nanoparticles is demonstrated. Porphyrin-phospholipids are used to coat upconversion nanoparticles in order to generate a new biocompatible material. The nanoparticles are characterized in vitro and in vivo for imaging via fluorescence, upconversion, positron emission tomography, computed tomography, Cerenkov luminescence, and photoacoustic tomography.

SUBMITTER: Rieffel J 

PROVIDER: S-EPMC4416944 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles.

Rieffel James J   Chen Feng F   Kim Jeesu J   Chen Guanying G   Shao Wei W   Shao Shuai S   Chitgupi Upendra U   Hernandez Reinier R   Graves Stephen A SA   Nickles Robert J RJ   Prasad Paras N PN   Kim Chulhong C   Cai Weibo W   Lovell Jonathan F JF  

Advanced materials (Deerfield Beach, Fla.) 20150114 10


Hexamodal imaging using simple nanoparticles is demonstrated. Porphyrin-phospholipids are used to coat upconversion nanoparticles in order to generate a new biocompatible material. The nanoparticles are characterized in vitro and in vivo for imaging via fluorescence, upconversion, positron emission tomography, computed tomography, Cerenkov luminescence, and photoacoustic tomography. ...[more]

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