Ontology highlight
ABSTRACT:
SUBMITTER: Little SC
PROVIDER: S-EPMC4417036 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Nature cell biology 20150406 5
Messenger RNA localization is a conserved mechanism for spatial control of protein synthesis, with key roles in generating cellular and developmental asymmetry. Whereas different transcripts may be targeted to the same subcellular domain, the extent to which their localization is coordinated is unclear. Using quantitative single-molecule imaging, we analysed the assembly of Drosophila germ plasm mRNA granules inherited by nascent germ cells. We find that the germ-cell-destined transcripts nanos, ...[more]