Which measures of adiposity predict subsequent left ventricular geometry? Evidence from the Bogalusa Heart Study.

ABSTRACT:

Background and aims

Left ventricular (LV) hypertrophy increases the risk of future cardiovascular events. The relationship between obesity in young adulthood and later LV geometry is unknown. We examined the association between long-term changes in measures of adiposity and subsequent LV geometry among 1073 young adults from the Bogalusa Heart Study.

Methods and results

Echocardiography-measured LV geometry was classified into normal (N = 796), concentric remodeling (N = 124), eccentric hypertrophy (N = 99), and concentric hypertrophy (N = 54) by integrating relative wall thickness and LV mass index. The mean age of our population was 38 years when the LV geometry was measured. Body mass index (BMI) increased by a mean of 4.9 kg/m(2) over a median of 20 years, waist circumfe

SUBMITTER: Hu T 

PROVIDER: S-EPMC4417354 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature