Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC4419559 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Wang Hengshuai H Jiao Shengchao S Chen Kerong K Zhang Xu X Zhao Linxiang L Liu Dan D Zhou Yu Y Liu Hong H
Beilstein journal of organic chemistry 20150330
We report a synthetic methodology for the construction of the fused heterocyclic compounds pyrido[2,1-b]quinazolin-9(1H)-ones and pyrrolo[2,1-b]quinazolin-9(1H)-ones through an AgOTf-catalyzed intramolecular alkyne hydroamination reaction. The methodology is applicable to a wide scope of substrates and produces a series of fused quinazolinone heterocycles in good to excellent yields. ...[more]