Chemotherapy for small cell lung cancer: a comprehensive review.
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ABSTRACT:
SUBMITTER: Karim SM
PROVIDER: S-EPMC4419639 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Chemotherapy for small cell lung cancer: a comprehensive review.
Karim Syed Mustafa SM Zekri Jamal J
Oncology reviews 20120301 1
Combination chemotherapy is the current strategy of choice for treatment of small cell lung cancer (SCLC). Platinum containing combination regimens are superior to non-platinum regimens in limited stage-SCLC and possibly also in extensive stage-SCLC as first and second-line treatments. The addition of ifosfamide to platinum containing regimens may improve the outcome but at the price of increased toxicity. Suboptimal doses of chemotherapy result in inferior survival. Early intensified, accelerat ...[more]
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