Transcriptional control of mitosis: deregulation and cancer.
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ABSTRACT:
SUBMITTER: Nath S
PROVIDER: S-EPMC4419714 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Transcriptional control of mitosis: deregulation and cancer.
Nath Somsubhra S Ghatak Dishari D Das Pijush P Roychoudhury Susanta S
Frontiers in endocrinology 20150505
Research over the past few decades has well established the molecular functioning of mitosis. Deregulation of these functions has also been attributed to the generation of aneuploidy in different tumor types. Numerous studies have given insight into the regulation of mitosis by cell cycle specific proteins. Optimum abundance of these proteins is pivotal to timely execution of mitosis. Aberrant expressions of these mitotic proteins have been reported in different cancer types. Several post-transc ...[more]
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