Ontology highlight
ABSTRACT:
SUBMITTER: Chinzei N
PROVIDER: S-EPMC4420284 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Chinzei Nobuaki N Hayashi Shinya S Ueha Takeshi T Fujishiro Takaaki T Kanzaki Noriyuki N Hashimoto Shingo S Sakata Shuhei S Kihara Shinsuke S Haneda Masahiko M Sakai Yoshitada Y Kuroda Ryosuke R Kurosaka Masahiro M
PloS one 20150505 5
The potential relationship between cell cycle checkpoint control and tissue regeneration has been indicated. Despite considerable research being focused on the relationship between p21 and myogenesis, p21 function in skeletal muscle regeneration remains unclear. To clarify this, muscle injury model was recreated by intramuscular injection of bupivacaine hydrochloride in the soleus of p21 knockout (KO) mice and wild type (WT) mice. The mice were sacrificed at 3, 14, and 28 days post-operation. Th ...[more]