Ontology highlight
ABSTRACT:
SUBMITTER: Giblin SP
PROVIDER: S-EPMC4422809 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Giblin Sean P SP Midwood Kim S KS
Cell adhesion & migration 20150101 1-2
Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very restricted pattern of expression but an enormously diverse range of functions. Here, we discuss the importance of deciphering the expression pattern of, and effects mediated by, different forms of this molecule in order to fully understand tenascin-C biology. We focus on both post transcriptional and post translational events such as splicing, glycosylation, assembly into a 3D matrix and proteolytic cleav ...[more]