Ontology highlight
ABSTRACT:
SUBMITTER: Oliver G
PROVIDER: S-EPMC4423164 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Oliver Georgina G Dean Olivia O Camfield David D Blair-West Scott S Ng Chee C Berk Michael M Sarris Jerome J
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology 20150401 1
<h4>Objective</h4>Obsessive compulsive and related disorders are a collection of debilitating psychiatric disorders in which the role of glutamate dysfunction in the underpinning neurobiology is becoming well established. N-acetyl cysteine (NAC) is a glutamate modulator with promising therapeutic effect. This paper presents a systematic review of clinical trials and case reports exploring the use of NAC for these disorders. A further objective was to detail the methodology of current clinical tr ...[more]