Ontology highlight
ABSTRACT:
SUBMITTER: Kuznetsov I
PROVIDER: S-EPMC4423227 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Kuznetsov Ilya I Filevich Jorge J Dong Feng F Woolston Mark M Chao Weilun W Anderson Erik H EH Bernstein Elliot R ER Crick Dean C DC Rocca Jorge J JJ Menoni Carmen S CS
Nature communications 20150423
Analytical probes capable of mapping molecular composition at the nanoscale are of critical importance to materials research, biology and medicine. Mass spectral imaging makes it possible to visualize the spatial organization of multiple molecular components at a sample's surface. However, it is challenging for mass spectral imaging to map molecular composition in three dimensions (3D) with submicron resolution. Here we describe a mass spectral imaging method that exploits the high 3D localizati ...[more]