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Meter-long multiblock copolymer microfibers via interfacial bioorthogonal polymerization.

ABSTRACT: High-molecular-weight multiblock copolymers are synthesized as robust polymer fibers via interfacial bioorthogonal polymerization employing the rapid cycloaddition of s-tetrazines with strained trans-cyclooctenes. When cell-adhesive peptide is incorporated in the tetrazine monomer, the resulting protein-mimetic polymer fibers provide guidance cues for cell attachment and elongation.

SUBMITTER: Liu S

PROVIDER: S-EPMC4423755 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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Meter-long multiblock copolymer microfibers via interfacial bioorthogonal polymerization.

Liu Shuang S Zhang Han H Remy Roddel A RA Deng Fei F Mackay Michael E ME Fox Joseph M JM Jia Xinqiao X

Advanced materials (Deerfield Beach, Fla.) 20150330 17

High-molecular-weight multiblock copolymers are synthesized as robust polymer fibers via interfacial bioorthogonal polymerization employing the rapid cycloaddition of s-tetrazines with strained trans-cyclooctenes. When cell-adhesive peptide is incorporated in the tetrazine monomer, the resulting protein-mimetic polymer fibers provide guidance cues for cell attachment and elongation. ...[more]

PMID: 25824805

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