Ontology highlight
ABSTRACT:
SUBMITTER: Shen H
PROVIDER: S-EPMC4426092 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Circulation research 20150323 10
<h4>Rationale</h4>Early graft inflammation enhances both acute and chronic rejection of heart transplants, but it is unclear how this inflammation is initiated.<h4>Objective</h4>To identify specific inflammatory modulators and determine their underlying molecular mechanisms after cardiac transplantation.<h4>Methods and results</h4>We used a murine heterotopic cardiac transplant model to identify inflammatory modulators of early graft inflammation. Unbiased mass spectrometric analysis of cardiac ...[more]