Dataset Information

Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.

ABSTRACT: This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The rigid leaflet rotation was driven by the transmitral flow and hence the leaflet dynamics were solved using fluid-structure interaction approach. The simulation results showed that the bileaflet mechanical heart valve at the mitral position behaved similarly to that at the aortic position. Sudden area expansion near the aortic root initiated a clockwise anterior vortex, and the continuous injection of flow through the orifice resulted in further growth of the anterior vortex during diastole, which dominated the intraventricular flow. This flow feature is beneficial to preserving the flow momentum and redirecting the blood flow towards the aortic valve. To the best of our knowledge, this is the first attempt to numerically model intraventricular flow with the mechanical heart valve incorporated at the mitral position using a fluid-structure interaction approach. This study facilitates future patient-specific studies.

SUBMITTER: Su B

PROVIDER: S-EPMC4427484 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.

Su Boyang B Kabinejadian Foad F Phang Hui Qun HQ Kumar Gideon Praveen GP Cui Fangsen F Kim Sangho S Tan Ru San RS Hon Jimmy Kim Fatt JK Allen John Carson JC Leo Hwa Liang HL Zhong Liang L

PloS one 20150511 5

This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The rigid leaflet rotation was driven by the transmitral flow and hence the leaflet dynamics were solved using fluid-structure interaction approach. The simulation results showed that the bileaflet mecha ...[more]

PMID: 25961285

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Project description:Filling ability is one of the prominent rheological properties of the self-compacting concrete (SCC), which has been studied in this research work deploying the functional behavior of the concrete through the studied funnel apparatus using the coupled ANSYS-SPH interface. Seven (7) model cases were studied and optimized. The aim of this numerical study is to propose a more sustainable mix of coarse and fine aggregates proportion that allows for most minimum flow time to enhance a more efficient filling of forms during concreting. The maximum size of the coarse aggregates considered is 20 mm and that of the fine aggregates is below 4 mm. The Bingham model properties for the multiphysics (SPH)-ANSYS models' simulation are; viscosity = 20 ≤ μ ≤ 100 and the yield stress = 50 [Formula: see text], standard flow time, t (s) ranges; 6 ≤ t ≤ 25 and the funnel volume is 12 L. The minimum boundary flow time, which represents the time it takes for the SCC to completely flow through a specified distance, typically measured in seconds was modeled for in the seven (7) model cases. The second case with 40% coarse mixed with 60% fine completely flowed out in 16 s, thus fulfilling the minimum flow time. This minimum flow time was considered alongside other relevant parameters and tests, such as slump flow, passing ability, segregation resistance, and rheological properties (stresses), to comprehensively assess the filling ability of SCC in this model. By considering these factors and the optimized mix (40%C + 60%F:16s), engineers and researchers can optimize the SCC mix design to achieve the desired flowability and filling performance for their specific construction applications. The multiphase optimized mix was further simulated using the coupled interface of the ANSYS-SPH platform operating with the CFX command at air temperature of 25 °C. The results show energy reduction jump at the optimized flow time. Ideally, the mix, 40%C + 60%F:16s has been proposed as the mix with the most efficient flow to achieve the filling ability for sustainable structural concrete construction.

Project description:Objective:The geometric configuration of the intraventricular tunnel is related to the re-intervention of left ventricular outflow tract stenosis after double outlet right ventricle (DORV) correction. Hemodynamic simulation was performed in order to study the influence of the geometric configuration of the IVT on the pressure difference. Methods:CT images of DORV were processed to reconstruct 3D models of left and right ventricular flow chambers and aortic valve orifice, and then the size and relative position of the aortic valve orifice and ventricular septal defect were determined. Twenty five groups of the idealized models were established according to orthogonal test design and computational fluid dynamics method was applied to simulate hemodynamics. Three factors of geometric configuration were considered for the study of their influences on the pressure difference. The first factor is the distance between the ventricular septal defect and the plane of the aortic valve (DSA), the second factor is the ejection angle of blood from left ventricle flowing into the IVT (ALT), and the third factor is the turning radius of the IVT (RTT). SPSS software was employed to perform the orthogonal analysis. Additionally, twelve models with different turning radii were established for hemodynamic analysis, with the turning radii increasing from 0 mm with an interval of 1 mm, so as to study the influence of turning radius on pressure difference of IVT. Results:The analysis of variance showed that only the change of RTT had a significant effect on the pressure difference (P = 0 < 0.05), while the change of DSA and ALT had no significant effect on the pressure difference (P = 0.459 > 0.05, P = 0.263 > 0.05). The pressure difference decreases with the increase of RTT. When RTT reaches 6 mm, the pressure difference gradually remains unchanged with the increase of RTT, and the rate of change is less than 5%. Conclusion:RTT in the IVT is the main factor affecting the pressure difference. A small RTT will lead to a large pressure difference in the IVT. When RTT increases to 6 mm, the pressure difference in the IVT remains nearly unchanged. When performing the right ventricular double outlet correction; the turning radius of the IVT should be about 6 mm to ensure relatively small pressure difference.

Dataset Information

Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.

Publications

Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.

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