Mathematical model of flagella gene expression dynamics in Salmonella enterica serovar typhimurium.
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ABSTRACT:
SUBMITTER: Jain K
PROVIDER: S-EPMC4427578 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
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Mathematical model of flagella gene expression dynamics in Salmonella enterica serovar typhimurium.
Jain Kirti K Pradhan Amit A Mokashi Chaitanya C Saini Supreet S
Systems and synthetic biology 20150204 1-2
Flagellar assembly in Salmonella is controlled by an intricate genetic and biochemical network. This network comprises of a number of inter-connected feedback loops, which control the assembly process dynamically. Critical among these are the FliA-FlgM feedback, FliZ-mediated positive feedback, and FliT-mediated negative feedback. In this work, we develop a mathematical model to track the dynamics of flagellar gene expression in Salmonella. Analysis of our model demonstrates that the network is ...[more]
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