Ontology highlight
ABSTRACT:
SUBMITTER: Kruer MC
PROVIDER: S-EPMC4429307 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
International review of neurobiology 20130101
Neuropathology plays a key role in characterizing the pathogenesis of neurodegenerative diseases including forms of neurodegeneration with brain iron accumulation (NBIA). Despite important differences, several genetically diverse forms of NBIA nevertheless share common features in addition to iron deposition, such as the presence of neuroaxonal spheroids. Multiple forms of NBIA also demonstrate tau or synuclein pathology, suggesting parallels with both Alzheimer and Parkinson diseases. This chap ...[more]