SnoRNAs are a novel class of biologically relevant Myc targets.
Ontology highlight
ABSTRACT:
SUBMITTER: Herter EK
PROVIDER: S-EPMC4430873 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
snoRNAs are a novel class of biologically relevant Myc targets.
Herter Eva K EK Stauch Maria M Gallant Maria M Wolf Elmar E Raabe Thomas T Gallant Peter P
BMC biology 20150416
<h4>Background</h4>Myc proteins are essential regulators of animal growth during normal development, and their deregulation is one of the main driving factors of human malignancies. They function as transcription factors that (in vertebrates) control many growth- and proliferation-associated genes, and in some contexts contribute to global gene regulation.<h4>Results</h4>We combine chromatin immunoprecipitation-sequencing (ChIPseq) and RNAseq approaches in Drosophila tissue culture cells to iden ...[more]
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