Ontology highlight
ABSTRACT:
SUBMITTER: Maia AF
PROVIDER: S-EPMC4431526 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Maia André F AF Tanenbaum Marvin E ME Galli Matilde M Lelieveld Daphne D Egan David A DA Gassmann Reto R Sunkel Claudio E CE van den Heuvel Sander S Medema René H RH
Scientific data 20150512
Kinesins are a superfamily of microtubule-based molecular motors that perform various transport needs and have essential roles in cell division. Among these, the kinesin-5 family has been shown to play a major role in the formation and maintenance of the bipolar mitotic spindle. Moreover, recent work suggests that kinesin-5 motors may have additional roles. In contrast to most model organisms, the sole kinesin-5 gene in Caenorhabditis elegans, bmk-1, is not required for successful mitosis and an ...[more]