Ontology highlight
ABSTRACT:
SUBMITTER: Gire SK
PROVIDER: S-EPMC4431643 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20140828 6202
In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to ~2000× coverage. We observed a rapid accumulation of interhost and intrahost genetic variation, allowing us to characterize patterns of viral transmission over the initial weeks of the epidemic. This West African variant likely diverged from central African lineages around 2004, crossed from Guinea to Sierra Leone in ...[more]