Ontology highlight
ABSTRACT:
SUBMITTER: Nakajima A
PROVIDER: S-EPMC4431830 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Nakajima Akio A Masaki Yasufumi Y Nakamura Takuji T Kawanami Takafumi T Ishigaki Yasuhito Y Takegami Tsutomu T Kawano Mitsuhiro M Yamada Kazunori K Tsukamoto Norifumi N Matsui Shoko S Saeki Takako T Okazaki Kazuichi K Kamisawa Terumi T Miyashita Taiichiro T Yakushijin Yoshihiro Y Fujikawa Keita K Yamamoto Motohisa M Hamano Hideaki H Origuchi Tomoki T Hirata Shintaro S Tsuboi Hiroto H Sumida Takayuki T Morimoto Hisanori H Sato Tomomi T Iwao Haruka H Miki Miyuki M Sakai Tomoyuki T Fujita Yoshimasa Y Tanaka Masao M Fukushima Toshihiro T Okazaki Toshiro T Umehara Hisanori H
PloS one 20150514 5
<h4>Background</h4>IgG4-related disease (IgG4-RD) is a new clinical entity of unknown etiology characterized by elevated serum IgG4 and tissue infiltration by IgG4-positive plasma cells. Although aberrancies in acquired immune system functions, including increases in Th2 and Treg cytokines observed in patients with IgG4-RD, its true etiology remains unclear. To investigate the pathogenesis of IgG4-RD, this study compared the expression of genes related to innate immunity in patients with IgG4-RD ...[more]