Ontology highlight
ABSTRACT:
SUBMITTER: Valsesia G
PROVIDER: S-EPMC4432064 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Valsesia Giorgia G Roos Malgorzata M Böttger Erik C EC Hombach Michael M
Journal of clinical microbiology 20150311 6
In this study, we introduce a new approach for determination of epidemiologic cutoffs (ECOFFs) and resistant-population cutoffs (RCOFFs) based on receiver operating characteristic (ROC) curves. As an example, the method was applied for determination of ECOFFs for seven different beta-lactam antibiotics and wild-type populations of Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae. In addition, RCOFFs were determined for bacterial populations with defined resistance mechanisms ("r ...[more]