Unknown

Dataset Information

0

Etest cannot be recommended for in vitro susceptibility testing of mucorales.


ABSTRACT: Amphotericin B and posaconazole susceptibility patterns were determined for the most prevalent Mucorales, following EUCAST (European Committee on Antimicrobial Susceptibility Testing) broth microdilution guidelines. In parallel, Etest was performed and evaluated against EUCAST. The overall agreement of MICs gained with Etest and EUCAST was 75.1%; therefore, Etest cannot be recommended for antifungal susceptibility testing of Mucorales. Amphotericin B was the most active drug against Mucorales species in vitro, while the activities of posaconazole were more restricted.

SUBMITTER: Caramalho R 

PROVIDER: S-EPMC4432123 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

altmetric image

Publications

Etest cannot be recommended for in vitro susceptibility testing of mucorales.

Caramalho Rita R   Maurer Elisabeth E   Binder Ulrike U   Araújo Ricardo R   Dolatabadi Somayeh S   Lass-Flörl Cornelia C   Lackner Michaela M  

Antimicrobial agents and chemotherapy 20150406 6


Amphotericin B and posaconazole susceptibility patterns were determined for the most prevalent Mucorales, following EUCAST (European Committee on Antimicrobial Susceptibility Testing) broth microdilution guidelines. In parallel, Etest was performed and evaluated against EUCAST. The overall agreement of MICs gained with Etest and EUCAST was 75.1%; therefore, Etest cannot be recommended for antifungal susceptibility testing of Mucorales. Amphotericin B was the most active drug against Mucorales sp  ...[more]

Similar Datasets

| S-EPMC4572526 | biostudies-literature
| S-EPMC6113460 | biostudies-literature
| PRJEB38234 | ENA
| S-EPMC3256011 | biostudies-literature
| S-EPMC3391364 | biostudies-literature
| S-EPMC6989064 | biostudies-literature
| S-EPMC11344908 | biostudies-literature
| S-EPMC4068533 | biostudies-literature
| S-EPMC3008459 | biostudies-literature
| S-EPMC6985724 | biostudies-literature