Ontology highlight
ABSTRACT:
SUBMITTER: Acosta N
PROVIDER: S-EPMC4432731 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Acosta Nicole N Pukatzki Stefan S Raivio Tracy L TL
Infection and immunity 20150330 6
Bacteria possess signal transduction pathways capable of sensing and responding to a wide variety of signals. The Cpx envelope stress response, composed of the sensor histidine kinase CpxA and the response regulator CpxR, senses and mediates adaptation to insults to the bacterial envelope. The Cpx response has been implicated in the regulation of a number of envelope-localized virulence determinants across bacterial species. Here, we show that activation of the Cpx pathway in Vibrio cholerae El ...[more]