An in situ Raman spectroscopy-based microfluidic "lab-on-a-chip" platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms.
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ABSTRACT:
SUBMITTER: Feng J
PROVIDER: S-EPMC4433399 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Publications
An in situ Raman spectroscopy-based microfluidic "lab-on-a-chip" platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms.
Feng Jinsong J de la Fuente-Núñez César C Trimble Michael J MJ Xu Jie J Hancock Robert E W RE Lu Xiaonan X
Chemical communications (Cambridge, England) 20150501 43
Pseudomonas aeruginosa biofilm was cultivated and characterized in a microfluidic "lab-on-a-chip" platform coupled with confocal Raman microscopy in a non-destructive manner. Biofilm formation could be quantified by this label-free platform and correlated well with confocal laser scanning microscopy. This Raman-microfluidic platform could also discriminate biofilms at different developmental stages. ...[more]
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