Ontology highlight
ABSTRACT:
SUBMITTER: Jackson D
PROVIDER: S-EPMC4433770 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Jackson Dan D Rollins Katie K Coughlin Patrick P
Research synthesis methods 20140227 3
Motivated by our meta-analytic dataset involving survival rates after treatment for critical leg ischemia, we develop and apply a new multivariate model for the meta-analysis of study level survival data at multiple times. Our data set involves 50 studies that provide mortality rates at up to seven time points, which we model simultaneously, and we compare the results to those obtained from standard methodologies. Our method uses exact binomial within-study distributions and enforces the constra ...[more]