Ontology highlight
ABSTRACT:
SUBMITTER: Park SY
PROVIDER: S-EPMC4435482 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Park So-Yeon SY Kim Hangun H Yoon Somy S Bae Jeong A JA Choi Seok-Yong SY Jung Young Do YD Kim Kyung Keun KK
Molecular therapy : the journal of the American Society of Gene Therapy 20140609 9
MicroRNAs are increasingly implicated in the modulation of the progression of various cancers. We previously observed that KAI1 C-terminal interacting tetraspanin (KITENIN) is highly expressed in sporadic human colorectal cancer (CRC) tissues and hence the functional KITENIN complex acts to promote progression of CRC. However, it remains unknown that microRNAs target KITENIN and whether KITENIN-targeting microRNAs modulate CRC cell motility and colorectal tumorigenesis. Here, through bioinformat ...[more]