Ontology highlight
ABSTRACT:
SUBMITTER: Paw I
PROVIDER: S-EPMC4435977 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Paw Ivy I Carpenter Richard C RC Watabe Kounosuke K Debinski Waldemar W Lo Hui-Wen HW
Cancer letters 20150318 1
Glioblastoma (GBM) is the most aggressive, deadliest, and most common brain malignancy in adults. Despite the advances made in surgical techniques, radiotherapy and chemotherapy, the median survival for GBM patients has remained at a mere 14 months. GBM poses several unique challenges to currently available treatments for the disease. For example, GBM cells have the propensity to aggressively infiltrate/invade into the normal brain tissues and along the vascular tracks, which prevents complete r ...[more]