Ontology highlight
ABSTRACT:
SUBMITTER: Bermingham ML
PROVIDER: S-EPMC4437376 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Bermingham M L ML Pong-Wong R R Spiliopoulou A A Hayward C C Rudan I I Campbell H H Wright A F AF Wilson J F JF Agakov F F Navarro P P Haley C S CS
Scientific reports 20150519
In this study, we investigated the effect of five feature selection approaches on the performance of a mixed model (G-BLUP) and a Bayesian (Bayes C) prediction method. We predicted height, high density lipoprotein cholesterol (HDL) and body mass index (BMI) within 2,186 Croatian and into 810 UK individuals using genome-wide SNP data. Using all SNP information Bayes C and G-BLUP had similar predictive performance across all traits within the Croatian data, and for the highly polygenic traits heig ...[more]