Ontology highlight
ABSTRACT:
SUBMITTER: Ishimwe E
PROVIDER: S-EPMC4437821 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Ishimwe Egide E Hodgson Jeffrey J JJ Passarelli A Lorena AL
Virology 20150317
The Cydia pomonella granulovirus open reading frame 46 (CpGV-ORF46) contains predicted domains found in matrix metalloproteases (MMPs), a family of zinc-dependent endopeptidases that degrade extracellular matrix proteins. We showed that CpGV-MMP was active in vitro. Autographa californica multiple nucleopolyhedrovirus (AcMNPV) expressing CpGV-ORF46 replicated similarly to a control virus lacking CpGV-ORF46 in cultured cells. The effects of AcMNPV expressing CpGV-MMP on virus infection in culture ...[more]