Ontology highlight
ABSTRACT:
SUBMITTER: Benjamini O
PROVIDER: S-EPMC4437921 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Benjamini Ohad O Jain Preetesh P Trinh Long L Qiao Wei W Strom Sara S SS Lerner Susan S Wang Xuemei X Burger Jan J Ferrajoli Alessandra A Kantarjian Hagop H O'Brien Susan S Wierda William W Estrov Zeev Z Keating Michael M
Leukemia & lymphoma 20141119 6
Patients with chronic lymphocytic leukemia (CLL) are known to have an increased incidence of second cancers, but the contribution of commonly used frontline therapies to the incidence of second cancers is unclear. We report on the characteristics, incidence, outcomes and factors associated with second cancers in 234 patients receiving fludarabine, cyclophosphamide and rituximab (FCR) based regimens in the frontline setting. The risk of second cancers was 2.38 times higher than the expected risk ...[more]