Ontology highlight
ABSTRACT:
SUBMITTER: Paganoni S
PROVIDER: S-EPMC4438106 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Paganoni Sabrina S Wills Anne-Marie AM
Journal of child neurology 20130510 8
Amyotrophic lateral sclerosis is a fatal neurodegenerative disease. Epidemiologic data suggest that malnutrition is a common feature in amyotrophic lateral sclerosis and being overweight or obese confers a survival advantage in this patient population. In amyotrophic lateral sclerosis mouse models, a high-fat diet has been shown to lead to weight gain and prolonged survival. However, little research has been conducted to test whether nutritional interventions might ameliorate the disease course ...[more]